Morphine commonly causes which ocular effect?

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Study for the INBDE Pharmacology Test. Sharpen your pharmacology knowledge with flashcards and multiple choice questions, each question is accompanied by hints and explanations. Prepare confidently for your exam!

Multiple Choice

Morphine commonly causes which ocular effect?

Explanation:
Opioids like morphine commonly cause miosis, a pinching of the pupil to a small, constricted size. This happens because opioids increase parasympathetic outflow to the pupillary sphincter via mu-receptor activity, leading to pupil constriction. Clinically, pinpoint pupils are a classic sign of opioid effect or overdose. In contrast, dilation (mydriasis) occurs with sympathetic activation or anticholinergic effects, not with morphine; ptosis and nystagmus aren’t typical features of opioid-induced eye changes.

Opioids like morphine commonly cause miosis, a pinching of the pupil to a small, constricted size. This happens because opioids increase parasympathetic outflow to the pupillary sphincter via mu-receptor activity, leading to pupil constriction. Clinically, pinpoint pupils are a classic sign of opioid effect or overdose. In contrast, dilation (mydriasis) occurs with sympathetic activation or anticholinergic effects, not with morphine; ptosis and nystagmus aren’t typical features of opioid-induced eye changes.

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